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Atherosclerosis and Cardiovascular Diseases

Proceedings of the Sixth International Meeting on Atherosclerosis and Cardiovascular Diseases held in Bologna, Italy, October 27–29,1986

Paperback Engels 2011 9789401079389
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

1985 and 1986 were milestones for those who study atherosclerosis. In those years took place the USA Consensus Conference, followed first by the Italian Consensus Conference and then by the European one. They marked the final solution to the "querelle" on cholesterol and ischemic cardiopathy. On the basis of the results obtained from the Coronary Primary Prevention Trial (CPPT), plasmatic cholesterol is now no longer considered "a" risk factor in cardiovas­ cular diseases, but "the cause" of atherosclerosis and its organ damages. This was also the basic statement that came out of the 6th International Congress on "Atherosclerosis and Cardiovascular Diseases". The meeting was attended by specialists from various countries representing different experimental ap­ proaches to the cardiovascular diseases, from basic research (receptor pathol­ ogy, apoproteins physiopathology); to epidemiology (both observational study and prevention); to pure cardiology in its aspects of physiopathology, diagnosis and therapy; to the new invasive and non-invasive diagnostic methods; and to the presentation of studies which correlate new variables (serotonin, en­ dogenous opioids) with the atheromasic disease. The final outcome of this re­ search is therapy, be it a pharmacological, nutritional and/or surgical one. Il­ lustrious names from five continents dealt with a wide a range of topics, and their presentations produced a wealth of data. The presentations contained in this volume are the "corpus" of the congress and will serve as a precise updat­ ing for all specialists, physicians and students.

Specificaties

ISBN13:9789401079389
Taal:Engels
Bindwijze:paperback
Aantal pagina's:571
Uitgever:Springer Netherlands
Druk:0

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Inhoudsopgave

Evaluation of the clinical significance of the discovery of the LDL receptor.- 1. Evaluation of the clinical significance of the discovery of the LDL receptor.- Social aspects of atherosclerosis.- 2. Social aspects of atherosclerosis.- Primary and secondary prevention of atherosclerosis and coronary heart disease.- 3. Primary and secondary prevention of atherosclerosis and coronary heart disease.- The “CNR Progetto Finalizzato Obiettivo 44 Progressione e/o regression” an update on studies in Italy.- 4. The “CNR Progetto Finalizzato Obiettivo 44 Progressione e/o regression” an update on studies in Italy.- Atherosclerosis and the “CNR Progetto Finalizzato Medicina Preventiva e Riabilitativa”.- 5. Atherosclerosis and the “CNR Progetto Finalizzato Medicina Preventiva e Riabilitativa”.- Cardiac and vascular surgery: results, perspectives and hopes.- 6. Cardiac and vascular surgery: results, perspectives and hopes.- Apoproteins - Clinical Aspects.- 7. Genetic basis of apolipoprotein disorders.- 8. Apolipoproteins in differential diagnosis of patients at high risk for atherosclerosis.- 9. Genetic and non-genetic control of apoprotein metabolism in cultured human cells.- 10. The plasma metabolism of apolipoprotein A-IV.- 11. Modified LDL in humans.- 12. Clinical aspects of lipoprotein disorders.- Fixed Versus Dynamic Stenosis: Possible Causes and Therapeutic Approaches.- 13. Fixed versus dynamic stenosis: possible causes and therapeutic approach.- 14. The epicardial coronary arteries at necropsy in acute myocardial infarction.- 15. Perspectives in the management of acute myocardial infarction.- 16. Atherosclerosis and ischaemic heart disease: surgical solutions.- Present Knowledge and Perspectives of Calcium Entry Blockers in the Management of Coronary Artery Disease.- 17. Effects of calcium antagonists and adrenergic antihypertensive drugs on cellular cholesterol metabolism.- 18. Blood platelets: their role in atherogenesis and arterial thrombosis and their inhibition, in particular by calcium antagonists.- Primary and Secondary Prevention: Different Experiences.- 19. Prevention of coronary heart disease - links with other chronic disorders.- 20. Therapy versus prevention of coronary heart disease.- 21. Prevention in Europe - facts, fallacies and future.- 22. Low linoleic acid - a new risk factor for coronary heart disease.- 23. The US National Cholesterol Education Program.- 24. The WHO European Multifactor Preventive Trial of CHD.- 25. Epidemiology and clinical features of hypertension in the elderly.- 26. Atherosclerosis precursors in children. The Bologna study. Preliminary data.- 27. From observational to intervention programmes. The Brisighella study.- Lipid Regulation in the Prevention of Coronary Heart Disease.- 28. Relationship of glucose intolerance and elevated triglyceride: implications for gemfibrozil.- 29. A comparison of different formulations and dosage administrations of gemfibrozil in types IIA and IIB hyperlipidemia.- 30. Coronary heart disease in Italy.- Diet: A Risk Factor and a Means of Prevention of Atherosclerosis and Coronary Heart Disease.- 31. Dietary fiber and lipid metabolism.- 32. Dietary and biochemical studies with textured soy proteins.- 33. Fats from marine animals in human nutrition and prevention of cardiovascular diseases.- 34. The influence of diet and drugs of cholesterol metabolism in the liver.- 35. Individuality of the response of serum cholesterol to dietary cholesterol.- 36. Familial hypercholesterolemia in Italy; plasma cholesterol evaluation and diagnostic insight.- Extra Coronary Atherosclerotic Vascular Diseases.- 37. Do atherosclerotic plaques regress spontaneously in humans?.- 38. Pathogenetic mechanisms of transient brain ischaemic attacks.- 39. Interrelations between the degree of lipid lowering effect and the rate of progression of atherosclerotic cardiovascular disease.- 40. Results of carotid endarterectomy.- New Technologies and New Diagnostic and Therapeutic Approaches to Cardiovascular Diseases.- 41. Haemostatic factors and lipoproteins in atherogenesis.- 42. Comparative evaluation of echographic and histomorphometric data of carotid endarterectomy samples.- 43. Correlative electron microscopy in the study of atherosclerosis.- 44. The role of oxygen free radicals in the ischaemia - reperfusion injury.- 45. Local and remote effects of acute ischaemic infarction on cerebral glucose metabolism in man.- Serotonin and the Cardiovascular System.- 46. Serotonin and cardiovascular disease.- 47. Ketanserin in the treatment of hypertension: clinical review.- 48. Platelets and platelet-related substances in the natural history of atherosclerosis. The role of serotonin.- 49. Prevalence and incidence of leg ischaemia in the general population.- Endogenous Opioids.- 50. Dynorphin-related peptides in central and peripheral tissues: distribution and possible functions.- 51. Aging brain and dementia: change in central opioids and ACTH.- 52. Relationship between endogenous opioids and the cardiovascular system: dynorphin measurement in the human heart: ß-endorphin plasmatic levels assay during acute pulmonary oedema.- Bezafibrate, Atherosclerosis and Ischaemic Heart Disease.- 53. Studies on DNA fragment length polymorphism of human apolipoprotein B gene.- 54. Porphyrins, tumors and atherosclerosis.- 55. Influence of physical exercise on plasma lipoprotein pattern in healthy subjects.- 56. Long-term experience with bezafibrate in different types of hyperlipidemia.- 57. Role of fibrinogen in atherosclerosis: therapeutic effects of bezafibrate in short-term treatment.- Nicotinic Acid Derivatives, Atherosclerosis and Ischaemic Heart Disease.- 58. Effects of Acipimox on in vivo insulin sensitivity in obese subjects and NID diabetics.- 59. The lipid-lowering effect of the acipimox: comparison with tiadenol and probucol.- 60. A controlled trial on the hypolipidemic effect of Acipimox in type IIA and IIB hyperlipoproteinemia.- 61. Effect of Acipimox on serum lipids and apoproteins in type II hyperlipoproteinemia.- 62. Long-term multicentre trial with acipimox in diabetic patients with hyperlipoproteinemia.- Acetylcarnitine and Ageing Brain Syndromes.- 63. Experimental pharmacological aspects in brain aging.- 64. Acute effects of L-acetylcarnetine (LAC) on quantitative EEG (QEEG) and visual evoked potentials (VEPS) in patients affected by senile, presenile and alcoholic dementia. Comparison with L-carnetine.- 65. The pharmacology of cognitive disturbances: problems and perspectives.- 66. L-Acetylcarnetine prevents the parkinsonian syndrome induced by MPTP in monkeys.- Non-Invasive Investigations of the Cardiovascular System.- 67. Nuclear magnetic resonance in the detection of the atherosclerotic lesion.- 68. Perspective and limits of emission tomography in cerebrovascular disorders.- 69. The real utility of nuclear magnetic resonance in cardiovascular diseases.- 70. B-Mode echography: A new approach to the epidemiology of atherosclerotic disease?.- 71. Cardiac doppler in the assessment of aortic valvular diseases.- 72. Myocardial ischemia in pediatric age: clinical pictures and non-invasive assessment.- 73. Extracranial carotid atherosclerosis evolution and stroke occurrence: Role of the echotomographic analysis.- 74. Pre- and post-operative echotomography and aortic endoarterectomy.

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