Kevin M.K. Bottomley,
David Bradshaw,
John S. Nixon
Metalloproteinases as Targets for Anti-Inflammatory Drugs
Gebonden Engels 1999 1999e druk 9783764358563
Verwachte levertijd ongeveer 9 werkdagen
Samenvatting
This volume describes recent research in the field of metalloproteinases (a family of enzymes that can catalyze tissue degradation), in particular their participation in autoimmune diseases such as rheumatoid arthritis, reviewing the latest developments in metalloproteinase inhibitor design and the current status of clinical candidates. This volume is intended not only for those active in research into metalloproteinases but also for those with an interest in inflammatory diseases. Thus it addresses both academic and industrial researchers.
Specificaties
ISBN13:9783764358563
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:207
Uitgever:Birkhäuser Basel
Druk:1999
Lezersrecensies
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Inhoudsopgave
Structural characteristics of the matrix metalloproteinases.- Matrix metalloproteinase inhibitors.- Role of stromelysin-1 in cartilage metabolism.- Matrix metalloproteinases in neuro-inflammatory disease.- Membrane type matrix metalloproteinases: Regulators of focal proteolysis.- Aggrecanase and cartilage proteoglycan degradation.- Overview of the biological roles of metalloproteinases in health and disease.- Adhesion molecule sheddases.- TNF? converting enzyme.
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